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DeCS
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Descriptor English:
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Receptor, Interferon alpha-beta
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Descriptor Spanish:
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Receptor de Interferón alfa y beta
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Descriptor Portuguese:
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Receptor de Interferon alfa e beta
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Synonyms English:
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Interferon alpha-beta Receptor
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Tree Number:
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D12.776.543.750.705.852.400.500
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Definition English:
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A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE. |
History Note English:
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2007(1993)
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Allowable Qualifiers English:
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Record Number:
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52342
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Unique Identifier:
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D053633
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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